1. Introduction to PCI and PCI Circuit Neuroscience

2. Editorial policy

2.1 Scope

2.2 Type of articles

2.3 Repeatability of science and open science

2.4 Ethics

3. Submission guidelines

3.1 Requirements

3.1.1 Deposition of the MS and supplementary information

3.1.2 Ethics

3.2 Formatting guidelines 

3.2.1 Word limits and formatting requirements

3.2.2 Manuscript structure and organization

3.3 Submitting a preprint

3.4 Submitting a preprint anonymously

4. The evaluation and recommendation process

4.1 Overview

4.2 Transparent review

4.3 Handling of manuscripts by recommenders

4.4 Appeals process

5. Fate of PCI-recommended preprints: PCI-friendly journals and the Peer Community Journal

5.1 PCI-friendly journals

5.2 The Peer Community Journal (expected launch in autumn 2021)

1. Introduction to PCI and PCI Circuit Neuroscience

2. Editorial policy​

2.1 Scope​​​

PCI Circuit Neuroscience will evaluate preprints, and to a lesser extent articles published in journals, dealing with Circuit Neuroscience and in particular with these subjects: neuronal circuits, neuronal assemblies, neuronal oscillations, neurophysiology, synaptic physiology, synaptic plasticity, neuronal biophysics, neuroanatomy, neuropharmacology, behavioural neuroscience, systems neuroscience.

The preprints submitted to PCI Circuit Neuroscience may describe empirical or theoretical studies, and be based on observations from experiments or nature, or previously acquired data. They may also report the results of verbal, computer or mathematical models. Studies of methodologies are also appreciated. Perspectives, reviews and opinions and comments on previously published articles are also welcome. 

PCI Circuit Neuroscience recommends only preprints of high scientific quality that are methodologically and ethically sound. To this end, PCI Circuit Neuroscience: 
- Requires data, computer codes and mathematical and statistical analysis scripts to be made available to reviewers and recommenders at the time of submission and to readers after recommendation. 
- Welcomes reproductions of studies. 
- Welcomes preprint submissions based on preregistrations (with or without prior review) 
- Welcomes preprints reporting negative results, provided that the questions addressed and the methodology are sound. 
- Does not accept submissions of preprints presenting financial conflicts of interest. Other conflicts of interest must be minimal and declared. 
- Ensures that, as far as possible, the recommenders and referees have no conflict of interest with the content or authors of the study evaluated. 

2.2 Type of articles

The articles recommended may be of different types: reviews, comments, opinion papers, research articles, data papers, technical notes, computer notes, etc. Preregistrations should be submitted to PCI Registered Reports.​

2.3 Repeatability of science and open science​

PCI wants to promote scientific repeatability and reliability to improve the overall robustness and integrity of our scientific conclusions. To this aim, PCI has set up three mandatory rules and makes two suggestions to authors:

Mandatory rules:​

​Articles recommended by PCI must provide the readers with: 
-Raw data, made available directly in the text or through an open repository, such as Zenodo, Dryad or some other institutional repository (see Directory of Open Access Repositories) with a DOI. Data must be reusable, and the metadata and accompanying text must, therefore, carefully describe the data. ​

-Details on the quantitative analyses (e.g. data treatment and statistical scripts in R, bioinformatic pipeline scripts, etc.) and details concerning simulations (scripts, codes) in the text or through an open repository, such as Zenodo, Dryad or some other institutional repository (see Directory of Open Access Repositories) with a DOI. The scripts or codes must be carefully described such that another researcher can run them. 
-Details on experimental procedures must be given in the text.​

Suggestions to authors:

​​​​-PCI encourages authors to submit preprints based on preregistrations: Authors may post their research questions and analysis plan to an independent registry before observing the research outcomes, and, thus, before writing and submitting their article. This provides a way of clarifying their hypotheses, avoiding confusing “postdictions” and predictions, and carefully planning appropriate statistical treatment of the data (e.g. see 10.1073/pnas.1708274114).​​​

-Preregistrations should be submitted to PCI Registered Reports

-PCI welcomes submissions proposing replication studies. All submissions are assessed according to the same criteria, provided that the article is considered interesting by the recommender handling it and the research question is judged to be scientifically valid.​​​

2.4 Ethics​

Peer Community In is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE). In addition:

• Financial conflicts of interest are forbidden, see the PCI code of conduct.
• Authors should declare any potential non-financial conflict of interest.

3. Submission guidelines

3.1 Requirements

3.1.1 Deposition of the MS and supplementary information

• Authors should first post their article on a preprint server, such as bioRxiv or arXiv (see details). When the article has appeared on this server, authors can submit their article to PCI Circuit Neuroscience.
• Raw data, statistical scripts in R, bioinformatic pipeline scripts, scripts and codes used for simulation or for statistical analyses and all other supplementary information must be deposited in an open repository, such as Zenodo, Dryad or some other institutional repository (see Directory of Open Access Repositories) with a DOI. 

3.1.2 Ethics

 Original or acceptable secondary publication

• No part of the manuscript (MS) has been published, except for passages that are properly cited.
• In the MS, original data are clearly distinguished from published data. All information extracted from other publications is provided with citations.

Authorship

• All people listed as authors of the MS meet the authorship criteria, i.e. they contributed substantially to study planning, data collection or the interpretation of results and wrote or critically revised the MS and approved its final submitted version and agree to be accountable for all aspects of the work (ICMJE 2017).

• All people listed as authors of the MS are aware of their authorship and have agreed to be listed.
• No person who meets the authorship criteria has been omitted.

Ethical experimentation and interpretation

• If the study reported in the MS involved human participants, it should meet the ethical principles of the Declaration of Helsinki (WMA 2013).
• If appropriate, the study reported in the MS should meet the Consensus Author Guidelines on Animal Ethics and Welfare for Veterinary Journals concerning humane treatment of animals and should be approved by an ethical review committee.
• In fields of research requiring approval from an ethics committee or institutional review board, the authors should generally ensure that all the necessary approvals have been obtained before submission.
• The authors should include a statement in the manuscript that informed consent was obtained, for experimentation with human subjects.
• The authors should do their best to avoid errors in experimental design, data presentation, interpretation, etc. However, should they nevertheless ​discover any serious error in the MS (before or after recommendation), they will alert PCI Circuit Neuroscience
• None of the data presented in the MS has been fabricated or distorted, and no valid data have been excluded. Images shown in figures have not been manipulated to make a false impression on readers.
• The study results have been interpreted objectively. Any findings that run contrary to the authors’ point of view are discussed in the MS.
• The article does not, to the best of the authors’ knowledge, contain anything that is libelous, illegal, infringes anyone’s copyright or other rights, or poses a threat to public safety.

Acknowledgements

• All sources of funding for the study reported in the MS are stated.
• All people who are not listed as authors but contributed considerably to the study reported in the MS or assisted in its writing (e.g. author’s editors, translators, medical writers) are mentioned in the Acknowledgements.
• All people named in the Acknowledgements have agreed to be mentioned. They are not, however, responsible for the final version of the
• Consent has been obtained from the authors of any unpublished data cited in the MS.
• The owners of the copyright to any previously published figures or tables have agreed to their inclusion in the MS.

Conflict of interest

• Financial conflicts of interest are forbidden, see the PCI code of conduct.
• Authors should declare any potential non-financial conflict of interest.

Reference Sources

https://www.ease.org.uk/wp-content/uploads/2018/11/doi.10.20316.ESE_.2018.44.e1.pdf

https://www.wma.net/wp-content/uploads/2016/11/DoH-Oct2013-JAMA.pdf

http://www.icmje.org/recommendations/

https://ethics.iit.edu/ecodes/node/5487

3.2 Formatting guidelines

3.2.1 Word limits and formatting requirements

Although PCI Circuit Neuroscience imposes no word limits or specific formatting requirements on submissions, authors are requested to respect the following guidelines to ​facilitate peer review:

• Lines must be numbered
• Tables and figures must be located in the main text, not at the end of the manuscript.
• All the abbreviations used in the article should be defined, except those obvious to non-specialists.
• As PCI Circuit Neuroscience does not copy-edit articles, authors should pay careful attention to typographical and other errors. A recommended article should be as close to perfect as possible in form, because it is a finished article.
• The text should be cohesive, logically organized, and, thus, easy to follow.
• The presence of all tables and figures, additional materials, the accessibility of the data, scripts and codes and accuracy of the references must be checked.

Manuscripts should be as concise as possible, but as long as necessary, to ensure that the description of the rationale and methods is clear and comprehensive, and that all methods are reproducible. Authors should ensure that they follow established formatting conventions for articles in their discipline. Authors who intend to publish their article in a journal afterward should also take note of any sectional or overall word limits or other formatting requirements applying to the journal trageted.

3.2.2 Manuscript structure and organization

Submissions should usually include the following sections (reviews, commentaries and opinions may have a different organization):

Title

• The title should be unambiguous, understandable to specialists in other fields, and reflect the content of the article

Authors

• Indicate full name and affiliation for each author. Provide e-mail addresses, at least for the corresponding author, and for the first authors if different.
• Authors are invited to indicate their ORCID.
• PCI Circuit Neuroscience welcomes anonymous submissions (see section 3.3). 

Abstract

• Should be concise and present the main findings of the study.
• Structured abstracts (e.g., Background, Methods, Results, Discussion) can be used.

Introduction

• The introduction should clearly explain the reasons for the study.
• The introduction should build on relevant recent and past researchperformed in the field.
• The research question/hypothesis/prediction should be clearly presented.

Materials and methods

• Details of experimental procedures and quantitative analyses must be made fully available to readers, in the text or through deposition in an open repository, such as Zenodo, Dryad or institutional repositories with a DOI.
• For specimen-based studies, complete repository information should be provided and institutional abbreviations should be listed in a dedicated subsection (if applicable). Specimens on which conclusions are based must be deposited in an accessible and permanent repository.

Results

• Data must be available to readers, in the article or through deposition in an open repository, such as Zenodo, Dryad or institutional repositories, with a DOI.
• The authors’ data and ideas should be clearly distinguished from those of other people and from the authors’ earlier publications. Citations should be provided whenever relevant.

Discussion

• The research questions should be answered and the main results should be compared with published data, as objectively as possible.
• Conclusions must be clearly stated and supported by the data.
• Interpretations are possible, but must be clearly identified as such.

Tables and figures

• Figures and tables should be easily understandable without reference to the main body of the article.
• Captions to tables and figures must be informative but concise.

Acknowledgements

Funding

• All sources of funding must be listed in a separate funding section.

Conflict of interest disclosure

• Authors should declare any potential non-financial conflict of interest (financial conflicts of interest are forbidden, see the PCI code of conduct).
• In the absence of competing interests, the authors should nevertheless add the following sentence to the “Conflict of interest disclosure” section: “The authors declare they have no conflict of interest relating to the content of this article.” If appropriate, this disclosure may be completed by a sentence indicating that some of the authors are PCI recommenders: “XXX is a recommender for PCI Circuit Neuroscience.”

Author contributions

• Author contributions should be clearly stated.
• Authors can use the CRediT Taxonomy to describe each author’s individual contributions: Conceptualization; Data curation; Formal analysis; Funding acquisition; Investigation; Methodology; Project administration; Resources; Software; Supervision; Validation; Visualization; Writing – original draft; Writing – review and editing.

Data, script and code availability

• Data, statistical scripts, command lines and simulation codes must be made available to readers. They should either be included in the article or provided as Supplementary Information.
• The Data Availability section must clearly indicate where and how data can be accessed.
• Wherever possible, data, scripts and codes should be provided in machine-readable formats. Avoid PDFs, other than for textual supplementary information.
• Metadata should accompany the data, to make the data understandable and reusable by the reader.

Supplementary information

• If applicable, list the documents attached to the manuscript as Supplementary Information.
• Supplementary Information should either be deposited in open repositories (such as Zenodo, Dryad, OSF, Figshare, Morphobank, Morphosource, Github, MorphoMuseuM, Phenome10k, etc.), or hosted by institutional repositories and accessible. If data are in an open or institutional repository, a reference to the data, with a DOI, must be provided in the reference list and in this "Data, script and code availability" section.

References

• Authors are free to use their preferred reference style, as long as usual bibliographic information is provided (e.g., Authors, Year, Title, Editor/Journal, Volume, Pages/DOI) and style is consistent.
• If available, the DOI of each reference must be provided.
• Author-year or numerical citation schemes can be used.
• All references cited in the text must be included in the reference section and listed either in alphabetical order (author-year format) or by order of appearance (numerical format).
• In accordance with the 10^th point of the Declaration on Research Assessment (DORA) signed by Peer Community In, authors are encouraged to cite the original research reporting new data and discoveries as the primary source of information, rather than the review articles discussing them (see more here).

3.3 Submitting a preprint

To submit an article, authors should first post it on a preprint server, such as bioRxiv or arXiv. Once the article has appeared on this server, the authors should click on the “Submit preprint” button on our website home page, for access to a very simple submission process.

During the submission process, authors will be asked to suggest between 5 and 10 recommenders who could handle the evaluation of their preprint. Recommenders are very similar to a journal editors. They are responsible for finding reviewers, collecting reviews, and making editorial decisions based on reviews. They may eventually recommend the article after one or several rounds of review.

Note that PCI Circuit Neuroscience is under no obligation to consider the submitted preprint. Only submitted preprints selected by a recommender enter the evaluation process. Although we cannot guarantee that the preprint will be reviewed, all possible efforts will be made to make this possible.

If, for some reason, authors have difficulty with the submission process, they can contact us at contact@cneuro.peercommunityin.org.

For more details on the step-by-step procedure, authors can consult the how to? section  

3.4 Submitting a preprint anonymously

4. The evaluation and recommendation process

4.1 Overview

1. Once the Managing Board has validated your submission, the recommenders you suggest receive an alert, drawing their attention to your preprint.
2. We cannot guarantee that your preprint will be reviewed, but all possible efforts will be made to make this possible. If no recommender – including all recommenders in your field of expertise – has initiated the evaluation of your preprint after 20 days, you will be notified by e-mail. If this happens, we suggest that you cancel your submission.
3. Alternatively, a recommender finding your preprint particularly interesting can decide to initiate the evaluation process. In this case, you will be notified by e-mail. The recommender will invite reviewers, so as to obtain at least two high-quality reviews. Note that the recommender and reviewers must declare that they have no conflict of interest of any kind with the content or the authors of your preprint – see the code of conduct.
4. One or several classic cycles of reviews/decision/authors’ response follow, eventually leading to the recommendation or rejection of the article. At each round of review, the recommender may decide to reject or recommend your article. Alternatively, the recommender may ask you to revise your article, generating another round of reviews. The recommender signs all decisions, whereas reviewers may choose to remain anonymous or to sign their reviews. The median time to the first decision is 45 days.
5. If the recommender eventually decides to reject your article, the reviews and decision will be sent to you, but will not be published or publicly released by PCI Circuit Neuroscience. They will be safely stored in our database, to which only the Managing Board has access.
6. Alternatively, if the recommender decides to recommend your article, PCI Circuit Neuroscience publishes a “recommendation” of your article. This recommendation is a short article, written and signed by the recommender, similar to a News & Views piece, describing the context of your study and explaining why the recommender found your article is particularly interesting. PCI Circuit Neuroscience will also publish all the editorial correspondence (reviews, recommender's decisions, authors’ replies).
7. Before the recommendation of your article goes online, you can upload a new version of your article onto the open archive with a PCI Circuit Neuroscience cover page, a PCI Circuit Neuroscience template of your article. You can also indicate (e.g. in the acknowledgment section) that this article has been peer reviewed and recommended by PCI Circuit Neuroscience.
8. Once PCI Circuit Neuroscience has published the recommendation text, your article becomes a valid reference that can be used by scientists and cited in scientific publications. You no longer need to publish your article in a ‘traditional’ journals, although you remain free to do so if you wish.

4.2 Transparent review

PCI Circuit Neuroscience publishes all reviews of recommended manuscripts, with reviewers choosing whether to sign their reviews or remain anonymous. All reviews and recommender decision letters are published on the PCI Circuit Neuroscience platform at the point of acceptance. Reviews of rejected submissions are sent to the authors, but are not published. Reviewers and recommenders are expected to adhere to the PCI code of conduct, avoiding abusive or discriminatory language in their comments. Reviews that are considered to violate the code of conduct may be edited by recommenders or the Managing Board, returned to the reviewer for editing, or discarded.

4.3 Handling of manuscripts by recommenders

4.4 Appeals process

Authors of rejected manuscripts can appeal against a PCI Circuit Neuroscience decision within 30 days of receiving it, by contacting us at contact@cneuro.peercommunityin.org. Appeals will be considered by the specialist recommender(s) that handled the manuscript and the PCI Circuit Neuroscience Managing Board. Decisions following appeal are final.

5. Fate of PCI-recommended preprints: PCI-friendly journals and the Peer Community Journal

The goal of PCI is to evaluate and recommend preprints, converting them into valid, citable final articles. The theoretical outcome is for PCI-recommended preprints to remain on preprint servers.

However, for various reasons, the authors of PCI-recommended preprints may prefer:

-To submit their preprint to a PCI-friendly journal (accepts the article with no further peer review, or provides the authors with a response in usually less than 5 days, or uses the PCI evaluation if appropriate)
-To submit their preprint to the Peer Community journal (published as is, free of charge)
-To submit their preprint to another journal

In the case of PCI submissions being recommended and eligible for multiple journals, the authors will make the final decision as to where the manuscript should be published. The journal chosen may be any PCI-friendly journal, other journals, or no journal if the authors prefer the article to be hosted solely on their preferred preprint server. In all cases, the reviews and decision letters for recommended submissions will be published on the PCI platform.​​

5.1 PCI-friendly journals

5.1.1 Journals committed to accepting PCI-recommended articles without further peer review

• These journal endorses the PCI review criteria and agrees to accept, without further peer review, any manuscript obtaining a positive final recommendation from PCI while also meeting any additional procedural requirements that do not require further scientific evaluation by these journals. Such additional requirements could include falling within a defined disciplinary scope. 
• Note that subjective judgments about the importance, novelty or timeliness of a research question are not relevant to the judgment of research quality at PCI and are not assessed as an additional requirement by these journals.
• These journals accept PCI recommended articles for publication even if the reviews performed by PCI are anonymous. 
• Similarly, these journals will not relitigate any scientific elements of the study that PCI has already approved.
• These journals agree to display clearly, on the homepage of the article, a note indicating that the evaluation process was carried out by PCI of the following type: 

Editor's note: This article has been reviewed and recommended by Peer Community in Evolutionary Biology: Mathieu Joron (2020) Studying genetic antagonisms as drivers of genome evolution. Peer Community in Evolutionary Biology, 100108. https://doi.org/10.24072/pci.evolbiol.100108 

5.1.2 Journals providing authors with a fast response

• These journals do not automatically accept PCI-recommended articles, but have agreed to the following commitment: once the article is submitted by the authors, the journal agrees to provide the authors with one of the following three responses, within a specified short turnaround time (e.g. 5 days):

1. Acceptance with minor modifications with no further peer-review, 
2. Need for further peer-review before decision,
3. Not interested.

• In case of acceptance, these journals agree to display clearly on the homepage of the article a note indicating that the evaluation process was carried out entirely or partly by PCI, of the following type: 

Editors' note: A previous version of this article was reviewed and recommended by Peer Community in Evolutionary Biology: Mathieu Joron (2020) Studying genetic antagonisms as drivers of genome evolution. Peer Community in Evolutionary Biology, 100108. https://doi.org/10.24072/pci.evolbiol.

5.1.3 Journals committed to using PCI evaluations if appropriate

• These journals do not automatically accept PCI-recommended articles but have agreed to the following commitment: The journal will consider submissions of articles recommended by a PCI and they may use PCI reviews and recommendations for their own review processes, if appropriate.
• In case of acceptance, these journals agree to display clearly on the homepage of the article a note indicating that the evaluation process was carried out entirely or partly by PCI, of the following type: 

Editors' note: A previous version of this article was reviewed and recommended by Peer Community in Evolutionary Biology: Mathieu Joron (2020) Studying genetic antagonisms as drivers of genome evolution. Peer Community in Evolutionary Biology, 100108. https://doi.org/10.24072/pci.evolbiol.100108

5.2 The Peer Community Journal (expected launch in autumn 2021)

Once an article is recommended by a PCI, the authors can opt to publish their article in the Peer Community journal.

This Peer Community journal is

• Unique = a single journal for all PCIs
• Free = diamond open access (free for authors and for readers).
• Exclusive = Publishes only preprints recommended by PCI 
• Unconditional = can publish all PCI recommended articles without further modification 
• Opt-in = only if the authors wish to publish in it
• Immediate = no delay between submission and publication 

This journal, created and funded by the PCI organization, is one of the PCI-partner journals. It is hosted by a not-for-profit publisher.

The Peer Community journal does not provide of copyediting or typesetting services.

The Peer Community journal is currently being evaluated by an international scientific database for indexing.